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尹德领教授

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尹德领,男,中南大学药理系教授。1995年获得复旦大学医学院博士学位。1995年于中国科学院上海细胞所德国马普实验室及1997年美国红十字会Holland Labs进行博士后研究。2000年至2002年于美国约翰霍普金斯大学任Research Fellow。2014年至今任美国东田纳西州立大学内科系和生命医学系终身教授,博士研究生导师及博士后导师。2016年至今任中南大学特聘教授。尹教授研究方向为免疫/干细胞对心脏损伤的保护及其机理(Toll样受体/microRNAs/心脏干细胞调控心脏损伤及修复),慢性中毒性休克的病变机理[慢性中毒性休克对microRNAs和长链非编码RNA(Longnon-coding RNA, IncRNA)的调控].尹教授先后在Nature, Journal of Experimental Medicine,Journal of Immunology, Journal of Biological Chemistry等SCI专业杂志发表学术论文80余篇。曾担任美国Life Science副主编。担任10余种SCI杂志包括Journal of BiologicalChemistry特约审稿人.

Selected Publications:

1.Yin D, Mufson R, Wang R, Shi. Y. 1999.Fas-mediated cell death promoted by opioids.Nature397(6716): 218.

2.Yin D, Zhang L, Wang R, Radvanyi L, HaudenschildC, Fang Q, Kehly M, Shi Y. 1999. Ligation of CD 28 in vivo induces CD40 ligandexpression and promotes B-cell survival.Journal of Immunology163:4328-4334.

3.Yin D, Tuthill D, Mufson R, Shi. Y. 2000. Chronic restraint stress promotes lymphocyte apoptosis through modulating CD95 expression.Journal of Experimental Medicine191: 1423-1428.

4.Zhang C, Zhou G, Li H, Zhang Q, Zhang T, Li J, Hou J, Liew C, Yin D. 2007. Transcriptional silencing of the TMS1/ASC tumor suppressor gene by epigenetic mechanism in hepatocellular carcinoma cells.Journal of Pathology.212(2):134-142.

5.Hu D, Wan L, Chen M, Caudle Y, LeSage G, Li Q, Yin D. 2014. Essential role of IL-10/STAT3 in chronic stress-induced immune suppression.Brain, Behavior, and Immunity. 36:118-127.

6.Zhao J, Feng Y, Yan H, Chen Y, Wang J, Chua B, Stuart C, Yin D. 2014. Beta-arrestin2/miR-155/GSK3beta regulates transition of 5'-azacytizine-induced Sca-1-positive cells to cardiomyocytes.Journal of Cellular and Molecular Medicine. 18 (8):1562-1570.

7.Li H, Hu D, Fan H, Zhang Y, LeSage G, Caudle Y, Stuart C, Liu Z, Yin D. 2014. Beta-Arrestin 2 negatively regulates Toll-like receptor 4 (TLR4)-triggered inflammatory signaling via targeting p38 MAPK and interleukin 10. Journal of Biological Chemistry. 289 (33): 23075-23085.

8.Qiu S, Feng Y, LeSage G, Zhang Y, Stuart C, He L, Li Y, Caudle Y, Peng Y, Yin D. 2015. Chronic morphine-induced microRNA-124 promotes microglial immunosuppression by modulating P65 and TRAF6.The Journal of Immunology. 194 (3):1021-1030.

9.Yin D, Yang X, Li H, Fan H, Zhang X, Feng Y, Stuart C, Hu D, Caudle Y, Xie N, Liu Z, LeSage G. 2016.β-arrestin 2 promotes hepatocyte apoptosis by inhibiting Aktprotein.Journal of Biological Chemistry. Jan 8;291(2):605-612.


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